How Sirtuins Increase Fat Loss and Reverse Aging (Applicable Tips)
weight loss November 25th. 2021, 3:58pm30% off Verso NMN (Today’s Sponsor) for Black Friday: http://www.ver.so/blackfriday
Longevity and Weight Loss at the Same Time – Sirtuins & Aging Genes
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References
https://www.nature.com/articles/nrm.2017.53
https://pubmed.ncbi.nlm.nih.gov/19046567/
https://academic.oup.com/jcem/article/101/3/1263/2804942
https://academic.oup.com/jcem/article/101/3/1263/2804942
https://www.frontiersin.org/articles/10.3389/fendo.2018.00449/full
https://pubmed.ncbi.nlm.nih.gov/17877786/
Timestamps ⏱
0:00 – Intro
0:53 – What are Sirtuins?
4:35 – Effect of Sirtuins on the Metabolism
10:25 – Recap
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November 25th, 2021 at 4:29 pm
Glad Thomas is linking Dr Sinclair’s science based research with longevity here.
November 25th, 2021 at 5:29 pm
Anyone else here younger than 25?
November 25th, 2021 at 5:36 pm
The acoustics in your voice really help relief my colon
November 25th, 2021 at 6:22 pm
bro i been slim all my life because i,m super shredded nonstop because i,m lit to legit
November 25th, 2021 at 7:13 pm
I appreciate a lot of the info you share, but you do kinda explain a little too much. You get knee-deep into all of these isolated things, making it all so very complex. Taking all these high-dollar supplements, things plucked from their original form and reconfigured, as if "science" can really best nature (hint, it can't … see our sick and obese ppl, and dying world, mostly because white coats thought they knew best, and still do). Really, you really think that's the best way? I can tell you this with certainty. Many of our "miracle" concoctions and protocols might show us some immediate good results (see the "Biggest Loser" peeps), but in the long-term cause horrors we can't at this point anticipate/imagine. See the world (and, again, those "Biggest Loser" peeps … abusing one's body, "no pain, no gain," excessive anything, not a good thing). Good rule of thumb, trust your "gut" over science-y sh*t (requires cultivating that right-brain/feminine energy, "intuition"…and distinguishing it from fear, and its cohort, ego-driven, god-complex, left/masculine-brain energy). Or just remember, "KISS" and what Einstein said, something 'bout keeping it simple. Most especially, if what you're doing is aligned with Nature, you're more likely on the right path. It's the only reason I'm now doing the "intermittent fasting." It makes sense to not eat early in the day, most animals in the wild don't.
November 25th, 2021 at 8:03 pm
I've been trying to fast but around the 18hr mark I get lightheaded and dizzy
November 25th, 2021 at 8:41 pm
Noticed fasting is slow weight loss for me (metabolism bleh). No exercise except 3 mile walk in a week. Noticed if eat sirt foods not the program my weight goes down. My dinner one avocado combined with a splash of ACV (with the mother) then mixed herb powders garlic,curry,pepper, and chipotle. Then add my three ounces chicken. Then in morning weight check it seems lower. Hopefully others can try this dinner plan and give their input of next morning weight. I do stop eating before 7 pm and 9 or 10 am will eat sometimes or if you grab snack after 7 no carbs but nibble on protein
November 25th, 2021 at 9:09 pm
Wait… anorexia has higher sirts? Despite the stress and malnourishment? I wonder what happens when they are forced to refeed in hospital?
November 25th, 2021 at 9:49 pm
I've also noticed subtle changes in my elders eating habits. They are more hungry and have cravings for high carb or junkfood items plus they become gradually less active in their day to day life due to changes in work, use of car etc
November 25th, 2021 at 10:20 pm
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November 25th, 2021 at 10:36 pm
Sinclair reverse aged . Would a 70-year-old mouse take a decade to go back to 35 or 35 years?
November 25th, 2021 at 11:27 pm
I tried to add the NMN supplement a to my cart but it’s not working. Something wrong with the link?
November 26th, 2021 at 12:21 am
Also I hate plant based milk, I just cannot have that
November 26th, 2021 at 1:09 am
Hi I am on a keto diet and have lost around 32 kg but I am starting to miss my normal milk coffee, can I have a cup of normal milk coffee with out sugar once a day if I keep my carb intake in check, or will I be kicked out of ketosis
November 26th, 2021 at 1:16 am
I appreciate the info. I somewhat need it dumbed down, though. I get lost in how fast you throw out the terms and acronyms.
November 26th, 2021 at 1:54 am
Fat loss takes work and eating less generally. There is no easy shortcut or product that is safe. People are always looking for the easy way.
November 26th, 2021 at 1:59 am
Hi and thank you for all the good info. I'm trying to get opinion on Ka' chavia. Lot ads im Leary of processed miracle products. Any thoughts? Stay well
November 26th, 2021 at 2:28 am
This was very fascinating, I appreciate the super deep dive you take on these subjects. So it seems like NAD production dictates all of it, for the action of both PARPs and Sirtuins, which are the keys to the city.